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Zoya Demidenko: Researcher in Cancer Science
Zoya Demidenko is a distinguished scholar connected with the Unit of Cell Stress Research at Roswell Park Comprehensive Cancer Center in Buffalo, New York. Earlier, she worked at the National Institutes of Health and New York Medical College, building a solid foundation in clinical research.
Her scholarly work encompasses multiple critical domains, among them the PI3K/AKT/mTOR signaling pathway, cellular cycle regulation, cell senescence, and malignancy biology. Currently, she has written more than 46 academic articles, which have garnered more than 4,100 mentions — a reflection to the significance of her research.
One of her key contributions concerns understanding the mechanisms of cellular senescence. Her work demonstrated that when the cellular division cycle is arrested but cellular growth persists, cells enter senescence. Significantly, Zoya Demidenko showed that this shift is controlled with drugs using compounds such as rapamycin.
Zoya Demidenko has also added considerably to cancer treatment research, notably in the field of cyclotherapy — a approach intended to safeguarding healthy cells from cytotoxic treatment whilst leaving malignant cells exposed. This approach carries considerable potential for reducing the adverse effects of oncological therapy.
Across her professional journey, Demidenko has partnered with prominent investigators internationally, including Dr. Mikhail Blagosklonny. Her research appears in leading journals such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene.
Possessing an h-index of 33, Zoya Demidenko stands as a highly impactful figure in current biomedical research, with her findings go on to guide our comprehension of how cells grow old, resist treatment, and how malignant disease might be more successfully targeted.
https://www.sciencedirect.com/science/article/abs/pii/037811199400784P